Bruce Alberts

Bruce Alberts

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  1. Fresco, J.R., Alberts, B.M., and Doty, P. Some molecular details of the secondary structure of ribonucleic acid. Nature 188, 98-101 (1960).
  2. Fresco, J.R. and Alberts, B.M. The accommodation of noncomplementary bases in helical polyribonucleotides and deoxyribonucleic acids. Proc. Natl. Acad. Sci. USA 46, 311-321 (1960).
  3. Alberts, B.M. Fractionation of nucleic acids in dextran-polyethylene glycol two-phase systems. Methods Enzymol. 12, 566-581 (1967).
  4. Alberts, B.M. Efficient separation of single-stranded and double-stranded deoxyribonucleic acid in a dextran-polyethylene glycol two phase system. Biochemistry 6, 2527-2532 (1967).
  5. Alberts, B.M. and Doty, P. Characterization of a naturally occurring, cross-linked fraction of DNA. I. Nature of the cross-linkage. J. Mol. Biol. 32, 379-403 (1968).
  6. Alberts, B.M. Characterization of a naturally occurring, cross-linked fraction of DNA. II. Origin of the cross-linkage. J. Mol. Biol. 32, 405-421 (1968).
  7. Alberts, B.M., Amodio, F.J., Jenkins, M., Gutmann, E.D., and Ferris, F.L. Studies with DNA-cellulose chromatography. I. DNA-binding proteins from Escherichia coli. Cold Spring Harb. Symp. Quant. Biol. 33, 289-305 (1969).
  8. Alberts, B.M. Function of gene 32-protein, a new protein essential for the genetic recombination and replication of T4 bacteriophage DNA. Fed. Proc. 29, 1154-1163 (1970).
  9. Yamamoto, K.R., Alberts, B.M., Benzinger, R., Lawhorne, L., and Treiber, G. Rapid bacterio-phage sedimentation in the presence of polyethylene glycol and its application to large-scale virus purification. Virology 40, 734-744 (1970).
  10. Alberts, B.M. and Frey, L. T4 bacteriophage gene 32: a structural protein in the replication and recombination of DNA. Nature 227, 1313-1318 (1970).
  11. Alberts, B. and Herrick, G. DNA-cellulose chromatography. Methods Enzymol. 21, 198-217 (1971).
  12. Alberts, B. On the structure of the replication apparatus. In “Nucleic Acid-Protein Interactions-Nucleic Acid Synthesis in Viral Infection,” Proceedings of the Miami Winter Symposia, 1971 (D.W. Ribbons, J.F. Woessner and J. Schultz, eds.), Vol. 2, pp. 128-143. North Holland Publishing Co., Amsterdam (1971).
  13. Huberman, J.A., Kornberg, A., and Alberts, B.M. Stimulation of T4 bacteriophage DNA polymerase by the protein product of T4 gene 32. J. Mol. Biol. 62, 39-52 (1971).
  14. Delius, H., Mantell, N.J., and Alberts, B. Characterization by electron microscopy of the complex formed between T4 bacteriophage gene 32-protein and DNA. J. Mol. Biol. 67, 341-350 (1972).
  15. Alberts, B., Frey, L., and Delius, H. Isolation and characterization of gene 5 protein of filamentous bacterial viruses. J. Mol. Biol. 68, 139-152 (1972).
  16. Sigal, N. and Alberts, B. Genetic recombination: the nature of a crossed strand-exchange between two homologous DNA molecules. J. Mol. Biol. 71, 789-793 (1972).
  17. Yamamoto, K.R. and Alberts, B.M. In vitro conversion of estradiol-receptor protein to its nuclear form: dependence on hormone and DNA. Proc. Natl. Acad. Sci. USA 69, 2105-2109 (1972).
  18. Barry, J. and Alberts, B. In vitro complementation as an assay for new proteins required for bacteriophage T4 DNA replication: purification of the complex specified by T4 genes 44 and 62. Proc. Natl. Acad. Sci. USA 69, 2717-2721 (1972).
  19. Barry, J., Hama-Inaba, H., Moran, L., Alberts, B., and Wiberg, J. Proteins of the T4 bacteriophage replication apparatus. In “DNA Synthesis in vitro” (R.D. Wells and R.B. Inman, eds.), pp. 195-214. University Park Press, Baltimore, Maryland (1973).
  20. Sigal, N., Delius, H., Kornberg, T., Gefter, M.L., and Alberts, B.A. DNA-unwinding protein isolated from Escherichia coli: Its interaction with DNA and with DNA polymerases. Proc. Natl. Acad. Sci. USA 69, 3537-3541 (1972).
  21. Alberts, B. Studies on the replication of DNA. In “Molecular Cytogenetics,” April 1973 Gatlinburg Symposium (B. Hamkalo and J. Papaconstantinou, eds.), pp. 233-251. Plenum Publishing Corp., New York (1973).
  22. Yamamoto, K.R. and Alberts, B. On the specificity of the binding of the estradiol receptor protein to deoxyribonucleic acid. J. Biol. Chem. 249, 7076-7086 (1974).
  23. Alberts, B. DNA-unwinding proteins and their role in the replication of DNA. In “Mechanism and Regulation of DNA Replication” (A.R. Kolber and M. Kohiyama, eds.), pp. 133-148. Plenum Press, New York (1974).
  24. Yamamoto, K.R. and Alberts, B. The interaction of estradiol-receptor protein with the genome: an argument for the existence of undetected specific sites. Cell 4, 301-310 (1975).
  25. Morris, C.F., Sinha, N.K., and Alberts, B.M. Reconstruction of bacteriophage T4 DNA replication apparatus from purified components: rolling circle replication following de novo chain initiation on a single-stranded circular DNA template. Proc. Natl. Acad. Sci. USA 72, 4800-4804 (1975).
  26. Alberts, B., Morris, C.F., Mace, D., Sinha, N., Bittner, M., and Moran, L. Reconstruction of the T4 bacteriophage DNA replication apparatus from purified components. In “DNA Synthesis and Its Regulation,” ICN-UCLA Symposium on Molecular and Cellular Biology (M. Goulian, P. Hanawalt and C.F. Fox, eds.), Vol. 3, pp. 241-269. W. H. Benjamin, Inc., Menlo Park (1975).
  27. Herrick, G. and Alberts, B. Purification and physical characterization of nucleic acid helix-unwinding proteins from calf thymus. J. Biol. Chem. 251, 2124-2132 (1976).
  28. Herrick, G. and Alberts, B. Nucleic acid helix-coil transitions mediated by helix-unwinding proteins from calf thymus. J. Biol. Chem. 25l, 2133-2141 (1976).
  29. Herrick, G., Delius, H., and Alberts, B. Single-stranded DNA structure and DNA polymerase activity in the presence of nucleic acid helix-unwinding proteins from calf thymus. J. Biol. Chem. 251, 2142-2146 (1976).
  30. Curtis, M.J. and Alberts, B. Studies on the structure of intracellular bacteriophage T4 DNA. J. Mol. Biol. 102, 793-816 (1976).
  31. Yamamoto, K.R. and Alberts B.M. Steroid receptors: elements for modulation of eukaryotic transcription. Annu. Rev. Biochem. 45, 721-746 (1976).
  32. Alberts, B., Worcel, A., and Weintraub, H. On the biological implications of chromatin structure. In “The Organization and Expression of the Eukaryotic Genome” (E.M. Bradbury and K. Javaherian, eds.), pp. 165-191. Academic Press, New York (l977).
  33. Manoil, C., Sinha, N., and Alberts, B. Intracellular DNA-protein complexes from bacteriophage T4-infected cells isolated by a rapid two-step procedure: characterization and identification of the protein components. J. Biol. Chem. 252, 2734-2741 (1977).
  34. Weintraub, H., Worcel, A., and Alberts, B.M. A model for chromatin based upon two symmetrically paired half nucleosomes. Cell 9, 409-417 (1976).
  35. Alberts, B., Barry, J., Bittner, M., Davies, M., Hama-Inaba, H., Liu, C.-C., Mace, D., Moran, L., Morris, C.F., Piperno, J., and Sinha, N.K. In vitro DNA replication catalyzed by six purified T4 bacteriophage proteins. In “Nucleic Acid-Protein Recognition,” Proceedings of the P & S Biomedical Sciences Symposium (H.J. Vogel, ed.), pp. Academic Press, New York (1977).
  36. Alberts, B. and Sternglanz, R. Recent excitement in the DNA replication problem. Nature 269, 655-661 (1977).
  37. Piperno, J.R. and Alberts, B.M. An ATP stimulation of T4 DNA polymerase mediated via T4 gene 44/62 and 45 proteins: the requirement for ATP hydrolysis. J. Biol. Chem. 253, 5174-5179 (1978).
  38. Piperno, J.R., Kallen, R.G., and Alberts, B.M. Analysis of a T4 DNA replication protein complex: studies of the DNA recognition site for T4 gene 44/62 and 45 protein-catalyzed ATP hydrolysis. J. Biol. Chem. 253, 5180-5185 (1978).
  39. Cousens, L.S., Gallwitz, D., and Alberts, B.M. Different accessibilities in chromatin to histone acetylase. J. Biol. Chem. 254, 17l6-l723 (1979).
  40. Liu, C.-C., Burke, R.L., Hibner, U., Barry, J., and Alberts, B.M. Probing DNA replication mechanisms with the T4 bacteriophage in vitro system. Cold Spring Harb. Symp. Quant. Biol. 43, 469-487 (1979).
  41. Morris, C.F., Hama-Inaba, H., Mace, D., Sinha, N.K., and Alberts, B. Purification of the gene 43, 44, 45, and 62 proteins of the bacteriophage T4 DNA replication apparatus. J. Biol. Chem. 254, 6787-6796 (1979).
  42. Morris, C.F., Moran, L.A., and Alberts, B.M. Purification of gene 41 protein of bacteriophage T4. J. Biol. Chem. 254, 6797-6802 (1979).
  43. Bittner, M., Burke, R.L., and Alberts, B.M. Purification of the T4 gene 32 protein free from detectable deoxyribonuclease activities. J. Biol. Chem. 254, 9565-9572 (1979).
  44. Palter, K.B. and Alberts, B.M. The use of DNA-cellulose for analyzing histone-DNA interactions: discovery of nucleosome-like histone binding to single-stranded DNA. J. Biol. Chem. 254, 11160-11169 (1979).
  45. Palter, K.B., Foe, V.E., and Alberts, B.M. Evidence for the formation of nucleosome-like histone complexes on single-stranded DNA. Cell 18, 451-467 (1979).
  46. Liu, L.F., Liu, C.-C., and Alberts, B.M. T4 DNA topoisomerase: a new ATP-dependent enzyme essential for the initiation of T4 bacterio-phage DNA replication. Nature 28l, 456-461 (1979).
  47. Liu, L.F., Liu, C.-C., and Alberts, B.M. Type II DNA topoisomerases: enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break. Cell 19, 697-707 (1980).
  48. Sinha, N.K., Morris, C.F., and Alberts, B.M. Efficient in vitro replication of double-stranded DNA templates by a purified T4 bacteriophage replication system. J. Biol. Chem. 255, 4290-4303 (1980).
  49. Hibner, U. and Alberts, B.M. The fidelity of DNA replication catalyzed in vitro on a natural DNA template by the T4 bacteriophage multienzyme complex. Nature 285, 300-305 (1980).
  50. Alberts, B.M., Barry, J., Bedinger, P., Burke, R.L., Hibner, U., Liu, C.-C., and Sheridan, R. Studies of replication mechanisms with the T4 bacteriophage in vitro system. In “Mechanistic Studies of DNA Replication and Genetic Recombination,” ICN-UCLA Symposium on Molecular and Cellular Biology (B.M. Alberts, ed.), Vol. 19, pp. 449-473. Academic Press, New York (1980).
  51. Burke, R.L., Alberts, B.M., and Hosoda, J. Proteolytic removal of the COOH terminus of the T4 gene 32 helix-destabilizing protein alters the T4 in vitro replication complex. J. Biol. Chem. 255, 11484-11493 (1980).
  52. Liu, C.C. and Alberts, B.M. Pentaribonucleotides of mixed sequence are synthesized and efficiently prime de novo DNA chain starts in the T4 bacteriophage DNA replication system. Proc. Natl. Acad. Sci. USA 77, 5698-5702 (1980).
  53. Liu, C.-C. and Alberts, B.M. Characterization of the DNA-dependent GTPase activity of T4 gene 4l protein, an essential component of the T4 bacteriophage DNA replication apparatus. J. Biol. Chem. 256, 2813-2820 (1981).
  54. Liu, C.-C. and Alberts, B.M. Characterization of RNA primer synthesis in the T4 bacteriophage in vitro DNA replication system. J. Biol. Chem. 256, 2821-2829 (1981).
  55. Belikoff, E., Wong, L.-J., and Alberts, B.M. Extensive purification of histone acetylase A, the major histone N-acetyl transferase activity detected in mammalian cell nuclei. J. Biol. Chem. 255, 11448-11453 (1980).
  56. Garcea, R.L. and Alberts, B.M. Comparative studies of histone acetylation in nucleosomes, nuclei and intact cells: evidence for special factors which modify acetylase action. J. Biol. Chem. 255, 11454-11463 (1980).
  57. Huang, C.-C., Hearst, J.E., and Alberts, B.M. Two types of replication proteins increase the rate at which T4 DNA polymerase traverses the helical regions in a single-stranded DNA template. J. Biol. Chem. 256, 4087-4094 (1981).
  58. Cousens, L.S. and Alberts, B.M. Accessibility of newly synthesized chromatin to histone acetylase. J. Biol. Chem. 257, 3945-3949 (1982).
  59. Tickle, C., Alberts, B., Wolpert, L., and Lee, J. Local application of retinoic acid to the limb bud mimics the action of the polarizing region. Nature 296, 564-566 (1982).
  60. Cullis, P.M., Wolfenden, R., Cousens, L.S., and Alberts, B.M. Inhibition of histone acetylation by N-[2-CoenzymeA)acetyl] spermidine amide, a multi-substrate analog. J. Biol. Chem. 257, 12165-12169 (1982).
  61. Alberts, B.M., Barry, J., Bedinger, P., Formosa, T., Jongeneel, C.V., and Kreuzer, K.N. Studies on DNA replication in the T4 bacteriophage in vitro system. Cold Spring Harb. Symp. Quant. Biol. 47, 655-668 (1983).
  62. Foe, V.E. and Alberts, B.M. Studies of nuclear and cytoplasmic behavior during the five mitotic cycles that precede gastrulation in Drosophila embryogenesis. J. Cell Science 61, 31-70 (1983).
  63. Nossal, N.G. and Alberts, B.M. The Mechanism of DNA replication catalyzed by purified bacteriophage T4 DNA replication proteins. In “Bacteriophage T4” (C. Mathews, E. Kutter, G. Mosig, and P. Berget, eds.), pp. 71-81. American Society for Microbiology, Washington, D.C. (1983).
  64. Bedinger, P. and Alberts, B.M. The 3’5′ proofreading exonuclease of bacteriophage T4 DNA polymerase is stimulated by other T4 DNA replication proteins. J. Biol. Chem. 258, 9649-9656 (1983).
  65. Formosa, T., Burke, R.L., and Alberts, B.M. Affinity purification of T4 bacteriophage proteins essential for DNA replication and genetic recombination. Proc. Natl. Acad. Sci. USA 80, 2442-2446 (1983).
  66. Bedinger, P., Hochstrasser, M., Jongeneel, C.V., and Alberts, B.M. Properties of the T4 bacterio-phage DNA replication apparatus: the T4 dda DNA helicase is required to pass a bound RNA polymerase molecule. Cell 34, 115-123 (1983).
  67. Thaller, C., Alberts, B.M., Goldsmith, E., Sprang, S., and Fletterick, R. Crystallization of the gene 45 protein from the DNA replication fork of bacteriophage T4. J. Biol. Chem. 259, 2568-2569 (1984).
  68. Kreuzer, K.N. and Alberts, B.M. Site-specific recognition of bacteriophage T4 type II DNA topoisomerase and E. coli DNA gyrase. J. Biol. Chem. 259, 5339-5346 (1984).
  69. Jongeneel, C.V., Formosa, T., and Alberts, B.M. Purification and characterization of the bacteriophage T4 dda protein, a DNA helicase that associates with the viral helix destabilizing protein. J. Biol. Chem. 259, 12925-12932 (1984).
  70. Jongeneel, C.V., Bedinger, P., and Alberts, B.M. Effects of the bacteriophage T4 dda protein on DNA synthesis catalyzed by purified T4 replication proteins. J. Biol. Chem. 259, 12933-12938 (1984).
  71. Jongeneel, C.V., Formosa, T., Munn, M., and Alberts, B.M. Enzymological studies on the T4 bacteriophage DNA replication proteins. In “Proteins Involved in DNA Replication” (U. Hubscher and S. Spadari, eds.). Advances in Experimental Medicine and Biology, Vol. 179, pp. 17-33. Plenum Publishing Corp., New York (1984).
  72. Mace, D.C. and Alberts, B.M. The complex of T4 bacteriophage gene 44 and 62 replication proteins form an ATPase that is stimulated by DNA and by T4 gene 45 protein. J. Mol. Biol. 177, 279-293 (1984).
  73. Mace, D.C. and Alberts, B.M. T4 DNA polymerase: rates and processivity on single-stranded DNA templates. J. Mol. Biol. 177, 295-311 (1984).
  74. Mace, D.C. and Alberts, B.M. Characterization of the stimulatory effect of T4 gene 45 protein and the gene 44/62 protein complex on DNA synthesis by T4 DNA polymerase. J. Mol. Biol. 177, 313-327 (1984).
  75. Walter, M. and Alberts, B.M. Intermediate filaments in tissue culture cells and early embryos of Drosophila melanogaster. In “Molecular Biology of Development,” UCLA Symposium on Molecular and Cellular Biology, New Series (R. Firtel and E. Davison, eds.), pp. 263-272. Alan R. Liss, New York (1984).
  76. Alberts, B.M. The DNA enzymology of protein machines. Cold Spring Harb. Symp. Quant. Biol. 49, 1-12 (1984).
  77. Formosa, T. and Alberts, B.M. The use of affinity chromatography to study proteins involved in bacteriophage T4 genetic recombination. Cold Spring Harb. Symp. Quant. Biol. 49, 363-370 (1984).
  78. Eichele, G., Tickle, C., and Alberts, B.M. Micro-controlled release of biologically active compounds in chick embryos: beads of 200 µm diameter for the local release of retinoids. Anal. Biochem. 142, 542-555 (1984).
  79. Alberts, B.M. Protein machines mediate the basic genetic processes. Trends in Genetics 1, 26-30 (1985).
  80. Burke, R.L., Munn, M., Barry, J., and Alberts, B.M. Purification and properties of the bacteriophage T4 gene 61 RNA priming protein. J. Biol. Chem. 260, 1711-1722 (1985).
  81. Foe, V.E. and Alberts, B.M. Reversible chromosome condensation induced in Drosophila embryos by anoxia: visualization of the interphase nuclear organization. J. Cell Biol. 100, 1623-1636 (1985).
  82. Kreuzer, K.N. and Alberts, B.M. A defective phage system reveals bacteriophage T4 replication origins that coincide with recombination hotspots. Proc. Natl. Acad. Sci. USA 82, 3345-3349 (1985).
  83. Alberts, B.M. Limits to growth: In biology, small science is good science. Cell 41, 337-338 (1985).
  84. Miller, K.G., Karr, T.L., Kellogg, D.R., Mohr, I.J., Walter, M., and Alberts, B.M. Studies on the cytoplasmic organization of early Drosophila embryos. Cold Spring Harb. Symp. Quant. Biol. 50, 79-90 (1985).
  85. Eichele, G., Tickle, C., and Alberts, B.M. Studies on the mechanism of retinoid-induced pattern duplications in the early chick limb bud: temporal and spatial aspects. J. Cell Biol. 101, 1913-1920 (1985).
  86. Alberts, B.M. DNA replication mechanisms. In “Genetic Chemistry: The Molecular Basis of Heredity,” Proceedings of the Robert A. Welch Foundation Conferences on Chemical Research XXIX, November 4-6, pp. 239-259. Houston, Texas (1985).
  87. Karr, T.L. and Alberts, B.M. Organization of the cytoskeleton in early Drosophila embryos. J. Cell Biol. 102, 1494-1509 (1986).
  88. Formosa, T. and Alberts, B.M. Purification and characterization of the T4 bacteriophage uvsX protein. J. Biol. Chem. 261, 6107-6118 (1986).
  89. Kreuzer, K.N. and Alberts, B.M. Characterization of a defective phage system for the analysis of bacteriophage T4 DNA replication origins. J. Mol. Biol. 188, 185-198 (1986).
  90. Cha, T.-A. and Alberts, B.M. Studies on the DNA helicase-RNA primase unit from bacteriophage T4. J. Biol. Chem. 261, 7001-7010 (1986).
  91. Selick, H.E., Barry, J., Cha, T.-A., Munn, M., Nakanishi, M., Wong, M.L., and Alberts, B.M. Studies on the T4 bacteriophage DNA replication system. In “Mechanisms of DNA Replication and Recombination,” UCLA Symposium on Molecular and Cellular Biology, New Series (T. Kelly and R. McMacken, eds.), pp. 183-214. Alan R. Liss, New York (1987).
  92. Formosa, T. and Alberts, B.M. DNA synthesis dependent on genetic recombination: characterization of a reaction catalyzed by purified bacteriophage T4 proteins. Cell 47, 793-806 (1986).
  93. Alberts, B.M. The Function of the Hereditary Materials: Biological Catalyses Reflect the Cell’s Evolutionary History. American Zoologist. 26:781-796 (1986).
  94. Kodadek, T. and Alberts, B.M. Stimulation of protein-directed strand exchange by a DNA helicase. Nature 326, 312-314 (1987).
  95. Alberts, B.M. Prokaryotic DNA replication mechanisms. Phil. Trans. R. Soc. Lond. B. 317, 395-420 (1987).
  96. Cha, T.-A. and Alberts, B.M. In vitro studies of the T4 bacteriophage DNA replication system. In “Cancer Cells 6: Eukaryotic DNA Replication.” Cold Spring Harbor Laboratory Press, pp. 1-10 (1988).
  97. Kodadek, T., Wong, M.L., and Alberts, B.M. The mechanism of homologous DNA strand exchange catalyzed by the bacteriophage T4 uvsX and gene 32 proteins. J. Biol. Chem. 263, 9427-9436 (1988).
  98. Kellogg, D., Mitchison, T., and Alberts, B.M. Behavior of microtubules and actin filaments in living Drosophila embryos. Development 103, 675-686 (1988).
  99. Selick, H.E., Kreuzer, K., and Alberts, B.M. The bacteriophage T4 insertion/substitution vector system: a method for introducing site-specific mutations into the virus chromosome. J. Biol. Chem. 263, 11336-11347 (1988).
  100. Cha, T.-A., and Alberts, B.M. The bacteriophage T4 DNA replication fork: only DNA helicase is required for leading-strand DNA synthesis by the DNA polymerase holoenzyme. J. Biol. Chem. 264, 12220-12225 (1989).
  101. Alberts, B. M. (1989). On the great excitement in Cell Biology – Introduction. American Zoologist, 29(2), 483-486..
  102. Miller, K.G. and Alberts, B.M. F-actin affinity chromatography: technique for isolating previously unidentified actin-binding proteins. Proc. Natl. Acad. Sci. USA 86, 4808-4812 (1989).
  103. Minden, J.S., Agard, D.A., Sedat, J.W., and Alberts, B.M. Direct cell lineage analysis in Drosophila melanogaster by time-lapse, three-dimensional optical microscopy of living embryos. J. Cell Biol. 109, 505-516 (1989).
  104. Herendeen, D.R., Kassavetis, G.A., Barry, J., Alberts, B.M., and Geiduschek, E.P. Enhancement of bacteriophage T4 late transcription by components of the T4 DNA replication apparatus. Science 245, 952-958 (1989).
  105. Bedinger, P., Munn, M., and Alberts, B.M. Sequence-specific pausing during in vitro DNA replication on double-stranded DNA templates. J. Biol. Chem. 264, 16880-16886 (1989).
  106. Cha, T.-A. and Alberts, B.M. Effects of the bacteriophage T4 Gene 41 and Gene 32 proteins on RNA primer synthesis: the coupling of leading- and lagging-strand DNA synthesis at a replication fork. Biochemistry 29, 1791-1798 (1990).
  107. Miller, K.G., Field, C.M., and Alberts, B.M. Actin-binding proteins from Drosophila embryos: a complex network of interacting proteins detected by F-actin chromatography. J. Cell Biol. 109, 2963-2975 (1989).
  108. Kellogg, D.R., Field, C.M., and Alberts, B.M. Identification of microtubule-associated proteins in the centrosome, spindle, and kinetochore of the early Drosophila embryo. J. Cell Biol. 109, 2977-2991 (1989).
  109. Bonne-Andrea, C., Wong, M.L., and Alberts, B.M. In vitro replication through nucleosomes without histone displacement. Nature 343, 719-726 (1990).
  110. Alberts, B. Mechanisms and enzymology of DNA replication. In “Structure and Function of Nucleic Acids and Proteins” (F. Y.-H. Wu and C.-W. Wu, eds.), pp. 223-237. Raven Press, New York (1990).
  111. Alberts, B. and Sternglanz, R. Chromatin contract to silence. Nature 344, 193-194 (1990).
  112. Alberts, B.M. Agenda for excellence. J. NIH Res. 2, 19-22 (1990).
  113. Alberts, B. and Weintraub, H. Obituary: Abraham Worcel (1938-1989). Cell 60, 695 (1990).
  114. Alberts, B.M. Recipes for replication. Nature 346, 514-515 (1990).
  115. Morrical, S.W. and Alberts, B.M. The uvsY protein of bacteriophage T4 modulates recombination-dependent DNA synthesis in vitro. J. Biol. Chem. 265, 15096-15103 (1990).
  116. Alberts, B.M. Skin-deep biology: a review of Life Science (Scott, Foresman, 1990 Ed.). Bookwatch Reviews, National Center for Science Education, Inc., Vol. 3, No. 6, 3-4 .
  117. Sullivan, W., Minden, J.S., and Alberts, B.M. daughterless-abo-like, a Drosophila maternal-effect mutation that exhibits abnormal centrosome separation during the late blastoderm divisions. Development 110, 311-323 (1990).
  118. Miller, K.G., Field, C.M., Kellogg, D.R., and Alberts, B.M. Use of actin filament and microtubule affinity chromatography to identify proteins that bind to the cytoskeleton. Methods Enzymol. 196, 303-319 (1991).
  119. Morrical, S.W., Wong, M.L., and Alberts, B.M. Amplification of snap-back DNA synthesis reactions by the uvsX recombinase of bacteriophage T4. J. Biol. Chem. 266, 14031-14038 (1991).
  120. Munn, M.M. and Alberts, B.M. The T4 DNA polymerase accessory proteins form a specific complex with the Gene 32 helix destabilizing protein on a primer-template junction. J. Biol. Chem. 266, 20024-20033 (1991).
  121. Munn, M.M. and Alberts, B.M. DNA footprinting studies of the complex formed by the T4 DNA polymerase holoenzyme at a primer-template junction. J. Biol. Chem. 266, 20034-20044 (1991).
  122. Alberts, B.M. Viewpoint: Elementary science education in the United States: how scientists can help. Curr. Biol. 1, 339-341 (1991).
  123. Formosa, T., Barry, J., Alberts, B.M., and Greenblatt, J. Using protein affinity chromatography to probe the structure of protein machines. Methods Enzymol. 208, 24-45 (1991).
  124. Kellogg, D.R., Sullivan, W., Theurkauf, W., Oegema, K., Raff, J.W., and Alberts, B.M. Studies on the centrosome and cytoplasmic organization in the early Drosophila embryo. Cold Spring Harb. Symp. 56, 649-662 (1991).
  125. Kellogg, D.R. and Alberts, B.M. Purification of a multiprotein complex containing centrosomal proteins from the Drosophila embryo by chromatography with low-affinity polyclonal antibodies. Molec. Biol. Cell 3, 1-11 (1992).
  126. Alberts, B. and Miake-Lye, R. Unscrambling the puzzle of biological machines: the importance of the details. Cell 68, 415-420 (1992).
  127. Li, J.J. and Alberts, B.M. News and Views: eukaryotic initiation rites. Nature 357, 114-115 (1992).
  128. Theurkauf, W.E., Smiley, S., Wong, M.L., and Alberts, B.M. Reorganization of the cytoskeleton during Drosophila oogenesis: implications for axis specification and intercellular transport. Development 115, 923-936 (1992).
  129. Hacker, K. and Alberts, B. Overexpression, purification, sequence analysis, and character-ization of the T4 bacteriophage dda DNA helicase. J. Biol. Chem. 267, 20674-20681 (1992).
  130. Selick, H.E., Stormo, G.D., Dyson, R.L., and Alberts, B.M. Analysis of five presumptive protein-coding sequences clustered between the primosome genes, 40 and 61, of bacteriophages T4, T2, and T6. J. Virol. 67, 2305-2316 (1993).
  131. Raff, J.W., Kellogg, D.R., and Alberts, B.M. Drosophila gamma-tubulin is part of a complex containing two previously identified centrosomal MAPs. J. Cell Biol. 121, 823-835 (1993).
  132. Theurkauf, W.E., Alberts, B.M., Jan, Y.N., Jongens, T.A. A central role for microtubules in the differentiation of Drosophila oocytes. Development 118, 1169-1180 (1993).
  133. Liu, B., Wong, M.L., Tinker, R.L., Geiduschek, E.P., and Alberts, B.M. The DNA replication fork can pass RNA polymerase without displacing the nascent transcript. Nature 366: 33-39 (1993).
  134. Alberts, B. 10-Step Recipe for Starting a Partnership Program. In “Science Education Partnerships, Manual for Scienctists and K-12 Teachers” (A. Sussman, ed.) pp. 15-18. UCSF, San Francisco (1993).
  135. Kellogg, D.R., Moritz, M., and Alberts, B.M. The centrosome and cellular organization. Annu. Rev. Biochem. 63: 639-674 (1994).
  136. Hacker, K. and Alberts, B. The slow dissociation of the T4 DNA polymerase holoenzyme when stalled by nucleotide omission: an indication of a highly processive enzyme. J. Biol. Chem. 269: 24209-24220 (1994).
  137. Hacker, K. and Alberts, B. The rapid dissociation of the T4 DNA polymerase holoenzyme when stopped by a DNA hairpin helix: a model for polymerase release following the termination of each Okazaki fragment. J. Biol. Chem., 269: 24221-24228 (1994).
  138. Alberts, B. How Targeted Should Research & Higher Education Be? Academic Medicine 69: 180-184 (March 1994).
  139. Liu, B., Wong, M.L., and Alberts, B. A transcribing RNA polymerase molecule survives DNA replication without aborting its growing RNA chain. Proc. Natl. Acad. Sci. U.S.A. 91: 10660-10664 (1994).
  140. Barry, J. and Alberts, B. Purification and characterization of bacteriophage T4 gene 59 protein: a DNA helicase assembly protein involved in DNA replication. J. Biol. Chem. 269: 33049-33062 (1994).
  141. Barry, J. and Alberts, B. A role for two DNA helicases in the replication of T4 bacteriophage DNA. J. Biol. Chem. 269: 33063-33068 (1994).
  142. Raff, J.W., Kellum, R. and Alberts, B. The Drosophila GAGA transcription factor is associated with specific regions of heterochromatin throughout the cell cycle. EMBO J. 13: 5977-5983 (1994).
  143. Alberts, B.M. Epilogue: Unsolved mysteries and the T4 paradigm. In Molecular Biology of Bacteriophage T4 (J.D. Karam, ed.). American Society for Microbiology Press (1994).
  144. Liu, B. and Alberts, B. Head-on collision between a DNA replication apparatus and RNA polymerase transcription complex. Science 267: 1131-1137 (1995).
  145. Kellum, R., Raff, J. and Alberts, B. Heterochromatin protein 1 distribution during development and during the cell cycle in Drosophila embryos. J. Cell. Science 108: 1407-1418 (1995).
  146. Kellum, R. and Alberts, B. Heterochromatin protein 1 is required for correct chromo-some segregation in Drosophila embryos. J. Cell. Science 108: 1419-1431 (1995).
  147. Moritz, M., Braunfeld, M., Fung, J., Sedat, J., Alberts, B. and Agard, D. Three-Dimensional Structural Characterization of Centrosomes from Early Drosophila Embryos. J. Cell Biology 130: 1149-1159 (1995).
  148. Alberts, Bruce. Harold M. Weintraub (1945-95). Nature 375: 19 (1995).
  149. Field, C. and Alberts, B. Anillin, a contractile ring protein that cycles from the nucleus to the cell cortex. J. Cell Biology 131: 165-178 (1995).
  150. Zheng, Y., Wong, M.-L., Alberts, B., and Mitchison, T. Nucleation of microtubule assembly by a -tubulin containing ring. Nature 378: 578-583 (1995).
  151. Moritz, M., Braunfeld, M., Sedat, J., Alberts, B., and Agard, D. Microtubule-nucleating sites in the centrosome are ring structures that contain -tubulin. Nature 378: 638-640 (1995).
  152. Oegema, K., Whitfield, W.G.F., and Alberts, B. The cell-cycle-dependent localization of the CP190 centrosomal protein is determined by the coordinate action of two separable domains. J. Cell Biology. 131: 1261-1273 (1995).
  153. Kellogg, D.R., Oegema, K., Raff, J., Schneider, K., and Alberts, B.M.  CP60: a microtubule-associated protein that is localized to the centrosome in a cell cycle-specific manner. Molec. Biol. Cell 6 (12):1673-1684 (1995)..
  154. Field, C., Al-Awar, O., Rosenblatt, J., Wong, M.L., Alberts, B., and Mitchison, T. A Purified Drosophila Septin Complex Forms Filaments and Exhibits GTPase Activity. J.Cell Biology 133 (3): 605-616. (1996) 
  155. Belanger, K., Mirzayan, C., Kreuzer, H., Alberts, B., and Kreuzer, K.  Two-dimensional gel analysis of rolling circle replication in the presence and absence of bacteriophage T4 primase. Nucleic Acids Research 24 (11): 2166-2175. (1996)
  156. Schrock, R.D. and Alberts, B. Processivity of the Gene 41 DNA Helicase at the Bacteriophage T4 DNA Replication Fork. J. Biol. Chem. 271: 16678-16682 (1996).
  157. Aroian, R.V., Field, C., Pruliere, C., Kenyon, C., and Alberts, B.M.. Isolation of actin-associated proteins from Caenorhabditis elegans oocytes and their localization in the early embryo. EMBO J.16 (7):1541-1549 (1997).
  158. Oegema, K., Marshall, W., Sedat, J., and Alberts, B. Two proteins that cycle asynchronously between centrosomes and nuclear structures: Drosophila CP60 and CP190. J. Cell Science 110 (14): 1573-1583 (1997).
  159. Alberts, B. The Cell as a Collection of Protein Machines: Preparing the Next Generation of Molecular Biologists. Cell 92: 291-294 (1998).
  160. Moritz, M., Zheng, Y., Alberts, B., and Oegema, K. Recruitment of the γ-tubulin ring complex to Drosophila salt-stripped centrosome scaffolds. J. Cell Biology 142 (3): 775-786 (1998).
  161. Moritz, M. and Alberts, B. Isolation of Centrosomes from Drosophila Embryos. Mitosis and Meiosis, Vol. 61, pp1-12 (C.L. Rieder, ed.), Academic Press, San Diego, CA (1999).
  162. Alberts BM, Ayala FJ, Botstein D, Frank E, Holmes EW, Lee RD, Macagno ER, Marrack P, Oparil S, Orkin SH, Rubenstein AH, Slayman CW, Sparling PF, Squire LR, von Hippel PH, and Yamamoto KR. Proposed changes for NIH’s center for scientific review. Science 1999 Jul 30;285 (5428): 666-7.
  163. Alberts, B. Are our universities producing too many PhDs? Trends in Cell Biology 9 (12): 73-75 (Millennium issue: December 1999).
  164. Alberts, B. Some Thoughts of a Scientist on Inquiry. In J. Minstrell & Emily H. van Zee, eds.) Inquiring into Inquiry Learning and Teaching in Science pp.-3-13. AAAS, Washington, DC.,: American Association for the Advancemnt of Science (2000).
  165. Alberts, B. Biomedical Research in the Next Century. Critical Issues in Global Health. (C. Everett Koop, Clarence E. Pearson & M. Roy Schwarz, eds.) pp. 287-296. Jossey-Bass, San Francisco, CA (2001).
  166. Alberts, B. DNA replication and recombination. Nature 421: 431-435 (2003).
  167. Alberts, B. Bridging the Gap Between Science and Society. The Relationship between Policy and Research in National Laboratories, Universities, Governement, and Industry. Rice University Baker Institute Policy Talk, Houston, Texas (2003).
  168. Alberts, B.M. A wake-up call: How failing a PhD led to a strategy for a successful scientific career. Nature 431, 1041 (2004).
  169. Alberts, B, The M.S. Swaminathan I know, Current Science Vol. 89, No. 2, 310-311 (2005).
  170. Alberts, B.M. A Wakeup Call for Science Faculty. Cell 123: 739-741 (2005).
  171. Alberts, B. The Globalization of Science. Project Syndicate (2008).
  172. Alberts, B. Restoring Science to Science Education. Issues In Science and Technology, p. 77-80, (2009).
  173. Alberts, B. ASCB 50th Anniversary Essay, Cell Biology: The Endless Frontier. Molecular Biology of the Cell, Vol. 21, 3785, (2010).
  174. Alberts, B. On the Science of Indian Rural Development. Agriculture Research, 1: 1 (2012).
  175. Alberts, B. The National Research Council’s “Framework for K-12 Science Education”: An Opportunity to Transform Science Education. The Opportunity Equation Website: http://opportunityequation.org/stem-focus/national-research-councils-framework (2012).
  176. Alberts, B. and Laymon, J. Opinion Piece in the San Jose Mercury News: Science Education Critical For Jobs Of Tomorrow (2012).
  177. Dr. Alberts’ Written Testimony Before the U.S. House of Representatives Committee on Science, Space, and Technology: Hearing on “Scientific Integrity and Transparency” (2013)
  178. Alberts, B., My Life as a Science Envoy. American Society for Microbiology Cultures Magazine, Vol. 1, Issue 1, 10-17 (2014).
  179. Alberts, B., Kirschner M., Tilghman S., and Varmus H. Rescuing US biomedical research from its systemic flaws. PNAS, Vol. 111, No. 16, 5773-5777 (2014).
  180. Alberts, B. Biographical Memoir of Paul Mead Doty, Proceedings of the American Philosophical Society, Vol. 158, No. 4 (2014).
  181. Alberts, B., Kirschner M., Tilghman S., and Varmus H. Opinion: Addressing systemic problems in the biomedical research enterprise. PNAS, Vol. 112, No. 7, 1912-1913 (2015).
  182. Alberts, B., Contributor to Muslim World Science Initiative Report of Zakri Task Force on Science at Universities of the Muslim World, “Science education in the United States: Some Lessons Learned,” London and Islamabad (2015).
  183. Alberts, B. and Kamb, A. Publishing confirming and non-confirming data, F1000Research, 5:135 (2016).
  184. Alberts, B., An Addiction to Education at All Levels, Cell, 167, 1-5 (2016).
  185. Alberts, B., Ensuring an Innovative and Productive Future for the Next Generation of Scientists, JAMA, Published online 2016.
  186. Barry, J., Wong, Mei Lie, and Alberts, B. In vitro reconstitution of DNA replication initiated by genetic recombination: a T4 bacteriophage model for a type of DNA synthesis important for all cells, Mol. Biol. Cell. Vol. 30, No. 1, 146-159 (2019).

 

Last updated: January 10, 2019 at 19:47 pm